Now I would like to thank specifically those persons who have helped me in the preparation of the book,
above and beyond the call of duty or of financial reward.
First, there is my wife, Miss Barbara, who is my best, and therefore, most formidable critic. She not only can check a fault in manuscript, but she can also analyze people with whom I deal. She uses no witches brew--—she is not Samanth--a—she uses intuition and what I call uncommon sense.
Next is my old pal and confere, Neal Thorpe, who with his usual aplomb and keen insight aided me greatly in the editing of the manuscript when I stayed with him on my frequent visits to the West Coast. Mr. Thorpe is vice-president of Man's Frontiers, an organization which I founded some years ago.
Man's Frontiers is "dedicated to explorations of the Unknown and the dissemination of facts about hitherto generally suppressed subjects." (See Appendixes)
While Man's Frontiers has not been fully activated due to lack of funds and the necessary time and energy, we plan its full-time activation shortly—with hoped-for assistance from those who believe in our purposes and that there are infinitely more worlds to explore, and who can well afford the cost of such an undertaking. We are convinced the world desperately needs such organizations which are seeking genuine answers without political or other self-serving overtones.
Another of our lieutenants who deserves special mention is Harold Salkin, secretary of Man's Frontiers, and long-time friend and associate. Harold went over the manuscript very carefully, as did Neal Thorpe and Miss Barbara—as did I, naturally. Harold also furnished many valuable suggestions.
Our four-member team and the eight-member team of researchers all examined the manuscript closely. In addition, Bantam s efficient staff of lawyers and editors--chief among whom was Grace Bechtold--steered the work safely to final publication. Damaris Rowland, Grace's assistant, deserves special credit for her coordination of the book through some periods when it seemed publication might be difficult. Also, my friend, Marc Jaffe, senior vice-president and editorial director at Bantam, merits praise for his efficient methods of expediting a long-delayed publication. He it was who never lost faith in my ability as an objective investigative reporter.
I would also like to thank two other friends, Donna Mayberry, a writer and English tutor, and Janice Moore, a TV and movie coordinator. Both assisted in organizing the mass of research material which I accumulated during the extended three-year period of Gerovital H3 research.
We know our readers, both general and professional, now have a book they can trust for veracity.
The book is one of which I am truly proud.
In a book of this nature which requires years of research and writing, there are necessarily hundreds of
persons to whom I am indebted. As much as I would like, I cannot list them all. (Several are listed specifically on the Acknowledgments page.)
However, the cooperation of the researchers involved in Gerovital H3 is most appreciated. Although the researchers were separated by many thousands of miles—from Massachusetts to Florida; from New York to California to Washington, D.C., to North Carolina--—they were united in a common cause: to find out the truth about Gerovital H3. And these places only mark the major research locations in the United States. Extensive research on the antidepressant, anti-aging qualities of Gerovital H3 has been going on in Romania and other European countries for nearly three decades. Yet it was in the United States with testing beginning in 1973 under Federal Food and Drug Administration supervision that the controversy over GH3 appears to have been resolved in a manner which must please all true scientists. This is due to multi-phase testing on humans including several "double-blind" studies. There is also confirmation in many laboratories on animals and on their cells and tissues--—all by brilliant researchers whose works cannot be contravened because the conclusions are so overwhelming when viewed in their entirety.
The rapport I established with these eminent researchers through close communication and frequent visits was most essential to the type of book I, as an independent writer, demand. The manuscript was submitted to those researchers working under the FDA-supervised project for their comments, corrections and insertions. Almost all made suggestions which I was grateful to incorporate in the book to avoid technical errors. Almost all were pleased with the book itself, which in turn, pleased me.
Several knowledgeable observers have predicted that Gerovital H3 may prove~ to be the third "wonder drug" of modern times--the other two being Penicillin and the Pill.
There have been many so-called "wonder drugs" in the last 30 years. Some have proved to be much less than wonderful and have been cast into the medical waste-heap. Some have proved useful for specific conditions and are included in the ever-growing list of worthwhile drugs doctors need for specific conditions--—these drugs can and do save many lives.
But it is difficult to imagine a near-universal antidote for depression and even harder to stretch the Imagination still further and conceive that such an agent could also be an antidote for the signs and symptoms of aging—and that it might actually be one of the long sought for substances necessary to counteract man's most ancient enemy.
As an investigative writer-reporter for many years without any real challenges to my published books or articles. I can say that I agree with the majority of GH3 researchers: that GH3 is a safe effective medication, proved clinically on thousands of people and now proved in the laboratory. It is no longer a theory. It is a fact.
Therefore, I believe that any investigative writer, after having examined the facts logically, objectively, should take a stand in defense of the truth of which he writes. He should present all sides, of course, but still have the courage to report the facts no matter what ensues. This I believe I have done in this book, and the researchers believe so, too, as they have stated.
We think we are on the eve of a great breakthrough in the history of the human race. Yet even if GH3 is only a unique antidepressant without side effects, we would still be achieving a major victory, for almost every member of our race suffers from depression, and as we progress toward our transfer to another dimension, depression and its apocalyptic partners are almost universally with us. We are now apparently in possession of Siegfried's Magic Ring—which while not yet conferring the immortality of the Gods, will enable us to undertake our lives on this planet with lengthened and broadened understanding; therefore with greater majesty and dignity when we are eventually faced with aging, old age and death.
Sandy Hook, Connecticut
Mr. Herbert Bailey has done a really outstanding job prescnting one of the most exciting and controversial stories in the long history of drug development.
Furthermore, he has told this story in a way that is highly readable and entertaining, to all readers from the man on the street to the highly trained scientist.
After reading this manuscript, I have come to the conclusion that Mr. Bailey has produced a balanced and completely factual account of the development of Gerovital H3. The sections describing the results of my reaserch as well as those describing the results of other Investigators with which I am intimately familiar, are completely accurate and precise.
M. David MacFarlane, Ph.D.
Director of Research
Institute of Research
The author has reported in a popular vein some of the results and implications of our work on the red cells of sickle cell anemia. It is important to emphasize that all of the work reported here on sickle cells has been done in the laboratory in test tubes, and up to this time (Gerovital H3 has not been administered to any patients with sickle cell anemia. It remains to be seen whether effective plasma levels of the drug can be safely attained. If this is not the case, then, as the author points out, treatment of the red cells with Gerovital outside the body remains a possibility. The tremendous gap in time, money and effort between laboratory practice and clinical application has yet to be filled, but the promise is clear and work will go on.
Richard F. Baker, Ph.D.
University of Southern California
School of Medicine
I want to take this occasion to say that we feel the reports you made of our research with Gerovital H3 are accurate and reliable. We found nothing in your manuscript which is either inaccurate or understated or which leaves out any significant material.
In our work as psychiatrists, we have over the years been constantly interested in finding various forms of treatment and medications to relieve people of mental, emotional strains and psychic trauma. We have used most of the medications which have come along the line from the pharmacologists and, to one degree or another, have begun to feel that Freud's early predictions that biochemical and neuropharmacological methods of treatment in certain psychiatric disorders for an answer to some of man's psychic distress would finally prove correct. We feel that we were fortunate in being able to carry on research on the value and uses of Gerovital H3 in the treatment of depressive disorders.
Our experience with this product has indicated that it is useful in the treatment of mild to moderate depressions and, more than that, gives us further opportunities to explore the reasons why people become depressed, both emotionally and chemically, and therefore gives us an opportunity to help, in the long run, in the search to a means of uncovering some of the secrets of the depressive disorders.
It is our hope the work begun with GH3 will only be the beginning in a series of researches done by us and others in the field in understanding depression, anxiety, and possibly some of the processes of aging. Most of the mysteries of aging are as yet unrevealed.
We are further reducing the data which we have obtained to elicit other factors involving the effects of Gerovital on both the body and depression.
Morton L. Kurland, M.D.
Max Hayman, M.D.
Desert Psychiatric Medical Group
Herbert Bailey has written the story of the procaine-based drug, Gerovital H3 (GH3), in an exciting fashion. Procaine is a local anesthetic drug that has been widely used for decades. It is quickly metabolized in the body into para-amino benzoic acid and an alcohol. Yet there have been persistent and growing claims that in the GH3 form it is more than a local anesthetic; that it is an anti-depressant, that it gives a sense of well being, that it is a restorer of youth and vigor and is beneficial for a number of disease states or dysfunctions that are concomitant with aging. Such claims suggest that a pharmaceutical fountain of youth is available and cause ecstasy in the minds of the critical and skepticism and accusations of charlatanism from the critical. A controversy exists that should be settled soon.
Our study (Cohen-Ditman report: see Chapter 10 and Appendix 3) of 41 patients treated in an open or non-blind fashion revealed that most claimed they felt less depressed, were more relaxed, had a sense of well being, and had a decrease in the discomforts of chronic inflammatory or degenerative diseases. These responses were made promptly and dramatically, but were mainly subjective. Certainly such broad and definite claims of benefit are intriguing and encouraging but caution in their interpretation is indicated. Our patients were familiar with the claims made for GH3 and expected symptom relief, increased vitality and a sense of well being. The possibility of a psychogenic effect cannot be ruled out by our study and such an effect could explain the improvement in our patients. The need for additional double-blind controlled studies is apparent. At this time it would seem unlikely that we have a pharmaceutical fountain of youth, but that we may well have a fairly safe and effective anti-depressant drug.
The writer of this book is to be commended for bringing this controversial story to the attention of all.
Keith S. Ditman, M.D., F.A.P.A.
As head of a team doing research on Gerovital H3, I found Herbert Bailey s book on the subject to be entirely accurate and reflective of the scope of our research.
Bert M. Zuckerman, Ph.D.
Professor of Nematology
University of Massachusetts
Laboratory of Experimental Biology
In writing the present book, Mr. Herbert Bailey has done a very outstanding job of presenting one of the most fascinating stories in the history of biomedical research on aging and aging retardation. After reading his manuscript, I came to the conclusion that Mr. Bailey has produced a well balanced and factual account of the exciting development of Gerovital H3. The sections describing the results of my research with Gerovital H3 at the Andrus Gerontology Center, University of Southern California, as well as those describing the results of other investigators with which I am familiar are accurate and precise.
Josef P. Hrachovec, M.D., D.Sc.
Return to Content List Continue - Chapter 1