"PROCAINE" VITAMIN H3
by Robert Koch, DSc
Procaine Hydrochloride was first synthesized in 1905 by a German chemist
Albert Einhorn. He was looking for a compound that would act as an anesthetic, would be non-toxic,
free of side effects, and would not be addictive. Dr. Einhorn was looking for a compound that could
replace cocaine as an anesthetic. Cocaine was being used at the time as an anesthetic. However, because
cocaine was toxic, addictive, and destructive to the central nervous system, its use was being outlawed.
Dr. Einhorn was able to produce a compound that demonstrated the properties he was looking for. This
new compound he named procaine. "Pro" means, in place of, and "caine" comes from the word cocaine.
Because of the similarity of the names and because they are both anesthetics, there is much confusion as
to the nature of procaine. Procaine when injected into the muscles acts as an anesthetic but when taken
orally in a complexed form procaine acts as a vitamin. Procaine HCl solutions, used as anesthetics, are
Chemically procaine is the PABA ester of the amino alcohol DEAE. PABA (p-amino-benzoic acid), is a "B"
vitamin. DEAE, (n,n diethylaminoethanol) is a biologically active precursor of the "B" vitamin choline.
(Fig. 1) Procaine is usually used in the form of the hydrochloride salt (procaine HCl) because it is
highly water soluble. Procaine hydrochloride, when taken orally, enters the body by being mainly
absorbed through the villi in the small intestine. Experiments show that the bulk of the procaine HCl
enters the bloodstream molecularly intact. In the blood stream procaine HCl is rapidly hydrolyzed by
the enzyme pseudo-cholinesterase into PABA and DEAE the two components of the procaine molecule. These
metabolites are removed by the liver, chemically changed, and excreted in the urine.
In the late 1940's Dr. Ana Aslan a Romanian cardiologist found that adding a
small amount of benzoic acid to the procaine solution stabilized some of the procaine enough to protect it
from the blood enzymes. This protected procaine which Dr. Aslan named Gerovital H3 or GH3 was found to be
very helpful in supplying PABA and DEAE to damaged and\or diseased cells. Ana Aslan named the procaine
vitamin H-3. GH3 is listed under H-3 in the Merck index.
Procaine HCl when combined with biologically active acids(1) such as folic
acid, biotin,ascorbic acid, pantothenic acid, citric acid and many other acids such as amino acids etc.,
acts as a vitamin or food supplement. The vitamin acids and other biologically active acids when complexed
with the procaine HCl molecule protect the procaine from the enzymes in the blood allowing the procaine to
enter the cells. These vitamin complexes help the cells assimilate and utilize nutrients more efficiently.
These complexed procaine compounds Dr. Koch named Vitacel (Vital Cell).
Procaine HCl (procaine hydrochloride) is the active ingredient in Gerovital
H3 (GH3) and in the Vitacels 3 through 8. Procaine HCl is broken down rapidly by enzymes in the blood
stream into PABA and DEAE. The PABA and DEAE are rapidly conjugated and removed from the blood and excreted
from the body. Because of this procaine HCl and its breakdown products (metabolites) are unable to get into
the cells in any great quantity to produce benefits. Procaine HCl will produce some benefits by itself, but
they are very limited.
However when procaine HCl is complexed properly (Koch process)(1) the
procaine HCl is protected from the action of the enzymes in the blood and tissues this protection gives the
procaine enough time to be transfered into the cells of the body where it helps the cells rebuild, repair,
and detoxify. This action of the procaine HCl complex is responsible for the remarkable improvements in
health that result from the use of GH3 and the Vitacel 3 - 8.
Many companies claim to make GH3. Based on my testing the only GH3 procaine
HCl based products that contain the active GH3 factor or properly complexed procaine HCl are Ana Aslanís
injectable GH3 and the Vitacels 3 through 8 produced by Nutritional Engineering, Ltd.. Some companies are
totally fraudulent in their claims quoting Ana Aslans case studies and my case studies and research to
validate their products which contain no procaine HCl or its complexes. Their products contain PABA and DMAE
which they claim produce procaine in the body. This is false because procaine contains no DMAE
(dimethylaminoethanol). In fact the DMAE when it enters the cells of the body is broken down and is oxidized
producing by products (metabolites) that are damaging and toxic to the cells ( i.e formaldehyde and methyl
alcohol). Whereas the DEAE (diethylaminoethanol) from the procaine HCl breaks down in the cells and is
oxidized producing acetyl groups that are very valuable for producing acetylcholine and other materials
necessary for cellular health.
Other companies produce GH3 and similar products that contain procaine HCl
and the other ingredients necessary to make GH3 and the Vitacels and list them on their labels but they
do not have a valid product. They mix the dry ingredients together and tablet them or put them in capsules
without first forming the procaine complexes. I like to use the example of making the candy called fudge.
Fudge contains sugar, cocoa, condensed milk, butter and a pinch of salt. If you mix all of these together
you have the correct formula but you only have a gritty cocoa in canned milk with a chunk of butter far from
being Fudge. However if you cook the ingedients to the soft ball stage and then allow it to cool , then
beat it properly to the right crystalline structure you end up with a delicious delight called fudge.
Procaine Based Nutriments (PBNs) as I prefer to call the procaine HCl
complexes or GH3 factor must be formed or the product wonít be very effective in helping cells heal and
overcome their problems. Effective GH3 products in tablets or capsules containing PBNs will show on their
labels not only the correct ingredients but they will also show the patent numbers(1) of the Koch process
for forming the complexes of procaine.